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Perlane® is an injectable filler used to treat deep areas of the face and contour the cheeks and chin. Made by the same company that produces Restylane®, Perlane® contains purified hyaluronic acid, a naturally-occurring substance in the skin that works with collagen to keep the skin elastic, supple and hydrated. It is hypoallergenic and so does not require a pre-treatment skin test. With its unique ability to bind with water, Perlane continues to perform up to 60% longer than collagen, but is used in the deeper layers of the face.